BoneXpert analyses an X-ray of a child's hand automatically, without any interference from a human. The main result is the Greulich Pyle bone age - TW2/3 bone ages can also be given. BoneXpert also reports the bone age standard deviation score. The X-ray can be of a left or a right hand and the hand can assume any rotation in the image plane. The analysis is automatically rejected, if it cannot be done reliably, e.g. if there is too much image postprocessing. Finally, the Bone Heath Index is determined from the cortical thicknesses in the metacarpals.
Product specifications Information source: Vendor
Last updated: March 31, 2020
Product name BoneXpert
Company Visiana
Subspeciality MSK
Modality X-ray
Disease targeted short stature, tall stature, early or late puberty, congenital adrenal hyperplasia, ortpoadic treatment planning, orthodontics, sports medicines, legal medicine
Key-features Bone age, Bone Health Index, Predicted adult height
Suggested use Without interference of a radiologist: AI-only diagnosis
Data characteristics
Population Children from age 0 years, all ethnicities
Input posterior anterior (PA) hand radiograph
Input format DICOM
Output annotated DICOM image, DICOM-encapsulated pdf report, Structured Report
Output format DICOM
Integration Integration in standard reading environment (PACS), Stand-alone third party application
Deployment Locally on dedicated hardware, Locally virtualized (virtual machine, docker)
Trigger for analysis Automatically, right after the image acquisition, On demand, triggered by a user through e.g. a button click, image upload, etc.
Processing time 3 - 10 seconds
CE Certified, Class I
FDA No or not yet
Market presence
On market since 03-2009
Distribution channels
Countries present (clinical, non-research use) 41
Paying clinical customers (institutes) 150
Research/test users (institutes) 13
Pricing model Pay-per-use, Subscription
Based on Number of analyses
Peer reviewed papers on performance

  • BoneXpert V1: Clinical review: An automated method for determination of bone age (read)

  • BoneXpert V1,2,3: A paediatric bone index derived by automated radiogrammetry (read)

  • BoneXpert V2: Automated determination of bone age from hand X-rays at the end of puberty and its applicability for age estimation (read)

  • BoneXpert V2: Clinical application of automatic Greulich-Pyle bone age in children with short stature (read)

  • BoneXpert V2: Prediction of Adult Height Based on Automated Determination of Bone Age (read)

  • BoneXpert V2: Validation and Reference Values of Automated Bone Age Determination for Four Ethnicities (read)

  • BoneXpert V2: Validation of automatic bone age rating in children with precocious and early puberty (read)

  • BoneXpert V2: Validation of automatic bone age determination in children with congenital adrenal hyperplasia (read)

Non-peer reviewed papers on performance

  • The RSNA Pediatric Bone Age Machine Learning Challenge, Radiology 2018 (read)

Other relevant papers

  • BoneXpert V2: Bone age assessment: automated techniques coming of age? (read)

  • Explainer video on the product (watch)

  • Explainer video on the architecture of the integration (watch)