2D Bone microarchitecture - QTS Score

QUIBIM

QUIBIM has developed a noninvasive post-processing module that characterizes the trabecular bone microarchitecture by providing bone volume percentage, trabecular thickness, separation and irregularity analysis. These imaging biomarkers are combined in a single score, the Quality of a Trabecular Structure (QTS) score, which allows to identify initial deterioration and assess treatment response with high sensitivity.
Product specifications Information source: Vendor
Last updated: March 10, 2020
General
Product name 2D Bone microarchitecture - QTS Score
Company QUIBIM
Subspeciality MSK
Modality X-ray
Disease targeted osteoporosis, oncology, ostopenia
Key-features Volume percentage, trabecular thickness, separation and fractal dimensions, and the Quality of a Trabecular Structure (QTS) Score
Suggested use During: perception aid (prompting all abnormalities/results/heatmaps), interactive decision support (shows abnormalities/results only on demand), Need to draw ROI
Data characteristics
Population Patients with bone degenerative diseases
Input X-Ray
Input format
Output One page structured report: ROI of trabecular bone, table of biomarkers, QTS score
Output format DICOM Secondary Capture / PDF
Technology
Integration Integration in standard reading environment (PACS), Integration via AI marketplace or distribution platform, Stand-alone third party application, Stand-alone webbased
Deployment Locally on dedicated hardware, Locally virtualized (virtual machine, docker), Cloud-based, Hybrid solution
Trigger for analysis Automatically after drawing ROI
Processing time > 10 minutes
Certification
CE Certified, Class IIa
FDA No or not yet
Market presence
On market since 01-2019
Distribution channels
Countries present (clinical, non-research use) 3
Paying clinical customers (institutes) <5
Research/test users (institutes) <5
Pricing
Pricing model License
Based on Number of installations, Number of analyses
Evidence
Peer reviewed papers on performance
Non-peer reviewed papers on performance
Other relevant papers Alberich-Bayarri A, et al. Reproducibility and accuracy in the morphometric and mechanical quantification of trabecular bone from 3 Tesla magnetic resonance images. Radiologia. 2014; 56: 27-34.

Alberich-Bayarri A, et al. Assesment of 2D and 3D fractal dimension measurements of trabecular bone from high-spatial resolution magnetic resonance images at 3 T. Med Phys. 2010; 37: 4930-7.

Alberich-Bayarri A, et al. In vivo trabecular bone morphological and mechanical relationship using high resolution 3 T magnetic resonance imaging. American Journal of Roentgenology. 2008. 1971: 721-726.