Liver Fat & Iron Concentration


Quibim has developed a VIRTUAL BIOPSY tool that analyzes MR volume datasets to provide a simultaneous quantification of iron, fat and water concentration for evaluating steatosis and iron overload improving the quality of the radiologist's reports and the accuracy of their diagnoses
Product specifications Information source: Vendor
Last updated: March 10, 2020
Product name Liver Fat & Iron Concentration
Company Quibim
Subspeciality Abdomen
Modality MR
Disease targeted Diffuse liver diseases, Cirrhosis, Fibrosis, Steatohepatitis, Hemochromatosis, Inflammatory activity
Key-features Liver segmentation, Quantification of PDFF and R2*
Suggested use Without interference of a radiologist: AI-only diagnosis
Data characteristics
Population Screening population
Input MRI MECSE Multi-Echo Chemical Shift Encoded
Input format
Output One-page structured report: PDFF and iron concentration parametric map, distribution table, statistics summary, steatosis grade
Output format DICOM Secondary Capture / PDF
Integration Integration in standard reading environment (PACS), Integration via AI marketplace or distribution platform, Stand-alone third party application, Stand-alone webbased
Deployment Locally on dedicated hardware, Locally virtualized (virtual machine, docker), Cloud-based, Hybrid solution
Trigger for analysis Automatically, right after the image acquisition
Processing time 1 - 10 minutes
Certified, Class IIa
No or not yet
Market presence
On market since 01-2019
Distribution channels
Countries present (clinical, non-research use) 4
Paying clinical customers (institutes) 5+
Research/test users (institutes) <5
Pricing model License
Based on Number of installations, Number of analyses
Peer reviewed papers on performance
Non-peer reviewed papers on performance
Other relevant papers França, M., Martí-Bonmatí, L., Porto, G., Silva, S., Guimaräes, S. and Alberich-Bayarri, Á. (2017). Tissue iron quantification in chronic liver diseases using MRI shows a relationship between iron accumulation in liver, spleen, and bone marrow. Clinical Radiology.

França, M., Alberich-Bayarri, Á. and Martí-Bonmatí, L. (2017). Accurate simultaneous quantification of liver steatosis and iron overload in diffuse liver diseases with MRI. Abdominal Radiology, 42(5), pp. 1434-1443.

Martí-Bonmatí, L., Alberich-Bayarri, Á. and Sánchez-González, J. (2012). Overload hepatitides: quanti-qualitative analysis. Abdom. Imaging. 37(2): 180-7.

Erturk, SM., Alberich-Bayarri, Á., Herrmann, KA., Martí-Bonmatí, L. and Ros, PR. (2009). Use of 3.0-T MR imaging for evaluation of the abdomen. Radiographics. 29(6): 1547-63.