QyScore

Qynapse

QyScore® is an advanced processing software for automatic labeling and volumetric quantification of segmented central nervous system structures. QyScore® produces a range of automated measures such as whole brain, white matter, grey matter by lobe, cerebellum, white matter abnormalities and brain substructures. Results are available with existing workflows through PACS, AV, AI viewers and in a dedicated 3D UI. QyScore® aims to decrease image reading variability and segmentation errors.

Information source: Vendor
Last updated: March 27, 2022

General Information

General
Product name	QyScore
Company	Qynapse
Subspeciality	Neuro
Modality	MR, PET
Disease targeted	Dementia, Multiple sclerosis, Alzheimer's disease, neuro-degenerative diseases
Key-features	Brain region quantification, comparison to reference population, white matter hyperintensities segmentation and evolution in time and space, report generation
Suggested use	During: perception aid (prompting all abnormalities/results/heatmaps), report suggestion After: diagnosis verification

Technical Specifications

Data characteristics
Population	Adults patients
Input	1.5T and 3T scanners for T1 MRI processing, and 3T scanners for T2FLAIR MRI
Input format	DICOM
Output	Segmentation overlay, report, 3D rendering, longitudinal charts, lesion load overlay, lesion evolution chart, normative database comparison charts
Output format	DICOM, DICOM SR, DICOM SEG, Fused DICOM, DICOM Secondary capture, pdf, .csv export of collection of patients, structured report metadata
Technology
Integration	Integration in standard reading environment (PACS), Integration via AI marketplace or distribution platform, Stand-alone webbased
Deployment	Locally on dedicated hardware, Locally virtualized (virtual machine, docker), Cloud-based, Hybrid solution
Trigger for analysis	Automatically, right after the image acquisition
Processing time	Depending on the technical workflow, T1, T1+T2 etc and the clinical needs

Regulatory

Certification
CE	Certified, Class IIa , MDD
FDA	510(k) cleared , Class II
Intended Use Statements
Intended use (according to CE)	QyScore® is an advanced processing and visualization software for automatic labeling and volumetric quantification of segmented central nervous system structures for patients older than 18 years of age. The software is intended to be used by medical personnel or neuroimaging trained personnel to support diagnosis of central nervous system diseases.

Market

Market presence
On market since	09-2017 (Europe) 12-2019 (USA)
Distribution channels	On-demand PACS agnostic (integration with several PACS vendors)
Countries present (clinical, non-research use)	5
Paying clinical customers (institutes)	< 10
Research/test users (institutes)	< 10 (also in clinical trials with pharma/CRO)
Pricing
Pricing model	Subscription
Based on	Number of installations

Evidence

Evidence
Peer reviewed papers on performance	Automatic segmentation of white matter hyperintensities: validation and comparison with state-of-the-art methods on both Multiple Sclerosis and elderly subjects (read) Validation of an automatic tool for the rapid measurement of brain atrophy and white matter hyperintensity in clinical routine setting: QyScore® (read)
Non-peer reviewed papers on performance
Other relevant papers