icobrain ms


icobrain ms helps physicians assess (sub)clinical disease activity in patients with multiple sclerosis.

icobrain ms allows for the objective assessment of lesion dissemination in space and time by:
- Quantifying and tracking FLAIR WM hyperintensities and T1 WM hypointensities

icobrain ms provides measures of brain volume changes by:
- Tracking annualized brain volume changes for whole brain and gray matter
- Comparing brain volumes and volume changes to an age-and gender-matched reference population.
Product specifications Information source: Vendor
Last updated: Nov. 9, 2021
Product name icobrain ms
Company icometrix
Subspeciality Neuro
Modality MR
Disease targeted Multiple sclerosis
Key-features White matter abnormality quantification, brain volume change, report generation
Suggested use During: perception aid (prompting all abnormalities/results/heatmaps), report suggestion
Data characteristics
Population multiple sclerosis patients
Input For MRI: 3D T1 weighted image and 3D FLAIR
Input format DICOM
Output Color-coded segmentation overlays, concise reports with reference statistics, pre-populated radiological reporting template
Output format DICOM
Integration Integration in standard reading environment (PACS), Integration RIS (Radiological Information System), Integration via AI marketplace or distribution platform
Deployment Cloud-based
Trigger for analysis Automatically, right after the image acquisition, On demand, triggered by a user through e.g. a button click, image upload, etc.
Processing time > 10 minutes
Certified, Class I , MDD
510(k) cleared, Class II
Market presence
On market since 2016
Distribution channels Blackford, GE Edison marketplace, Nuance AI marketplace
Countries present (clinical, non-research use) 23
Paying clinical customers (institutes) >100
Research/test users (institutes) >300
Pricing model Subscription
Based on Number of analyses
Peer reviewed papers on performance

  • Reliable measurements of brain atrophy in individual patients with multiple sclerosis (read)

  • Two Time Point MS Lesion Segmentation in Brain MRI: An Expectation-Maximization Framework (read)

  • icobrain ms 5.1: Combining unsupervised and supervised approaches for improving the detection of multiple sclerosis lesions (read)

Non-peer reviewed papers on performance
Other relevant papers

  • A Novel Digital Care Management Platform to Monitor Clinical and Subclinical Disease Activity in Multiple Sclerosis (read)