Hevi AI Prostate Zonal Segmentation

About

Editors:

joeran.bosma

krgz.ahmet1

Contact email:

krgz.ahmet@hotmail.com

Image Version:

fc63b5a0-0757-422a-9f58-a0c6b4fdced7 — Feb. 26, 2023

Associated publication:

Karagoz A, Seker ME, Yergin M, et al.. Prostate Lesion Estimation using Prostate Masks from Biparametric MRI. arXiv. Published online January 25, 2023.

Summary

This model segments the central zone + anterior stroma + transition zone (TZ), and peripheral zone (PZ). The model requires a NIFTI MR image as input and creates a probability map and segmentation mask as output. The model is based on nnUnet.

Mechanism

This algorithm is a deep learning-based model (nnU-Net model). We trained these models with a total of 204 prostate T2 MRI scans paired with a manual prostate segmentation. These scans were sourced from ProstateX. Annotations for ProstateX cases were retrieved from https://github.com/rcuocolo/PROSTATEx_masks/.

Input:

Datatype: Transverse T2 MR image of the prostate
File format: NIFTI image
Target group: Male patients

Output:

Results: Prostate zonal segmentation (segmentation), Softmax prostate peripheral zone segmentation (probabilistic map), Softmax prostate central zone segmentation (probabilistic map)
Source code: https://github.com/ahmetkrgztr/HeviAI_picai/tree/main/AbdomenMRUS-prostate-segmentation

Interfaces

This algorithm implements all of the following input-output combinations:

Inputs Outputs

	Inputs	Outputs
1	Transverse T2 Prostate MRI Description Transverse T2 MRI of the Prostate Kind Image Read from `/input/images/transverse-t2-prostate-mri/<uuid>.mha` or `/input/images/transverse-t2-prostate-mri/<uuid>.tif` Transverse T2 Prostate MRI	Prostate Zonal Segmentation Description Zonal segmentation of the prostate where 1 is the Peripheral Zone, 2 is the Central Gland, 3 is the Prostatic Urethra, and 4 is the Anterior Fibromuscular Stroma. Kind Segmentation Write to `/output/images/prostate-zonal-segmentation/<uuid>.mha` or `/output/images/prostate-zonal-segmentation/<uuid>.tif` Prostate Zonal Segmentation Softmax Prostate Peripheral Zone Segmentation Description Single-class heatmap of prostate peripheral zone segmentation, with each voxel indicating the likelihood in the range [0, 1] Kind Heat Map Write to `/output/images/softmax-prostate-peripheral-zone-segmentation/<uuid>.mha` or `/output/images/softmax-prostate-peripheral-zone-segmentation/<uuid>.tif` Softmax Prostate Peripheral Zone Segmentation Softmax Prostate Central Gland Segmentation Description Single-class heatmap of prostate central gland segmentation, with each voxel indicating the likelihood in the range [0, 1] Kind Heat Map Write to `/output/images/softmax-prostate-central-gland-segmentation/<uuid>.mha` or `/output/images/softmax-prostate-central-gland-segmentation/<uuid>.tif` Softmax Prostate Central Gland Segmentation

Validation and Performance

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Uses and Directions

This algorithm was developed for research purposes only. This algorithm is intended to be used only on prostate T2 MRI examinations.
This model is intended to be used by radiologists for predicting prostate volume in biparametric MRI examinations. The model is not meant to guide or drive clinical care.

Warnings

Even if used appropriately, clinicians using this model can estimate prostate volume incorrectly.
This model is not designed to guide clinical diagnosis and treatment for prostate cancer.

Common Error Messages

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Information on this algorithm has been provided by the Algorithm Editors, following the Model Facts labels guidelines from Sendak, M.P., Gao, M., Brajer, N. et al. Presenting machine learning model information to clinical end users with model facts labels. npj Digit. Med. 3, 41 (2020). 10.1038/s41746-020-0253-3