| 1 |
-
- Slug
structured-prompt- Description
- A (JSON) structured prompt that orchestrates an algorithm.
- Kind
- Anything
- Read from
-
/input/structured-prompt.json
- Example file
- Download an example.
- Example value
-
{
"key": "value",
"None": null
}
Structured Prompt
-
- Slug
prostate-modality-level-neural-representations- Description
- A collection of optional neural representations of prostate-related modalities. Contains "MRI image", "Biopsy slide" and/or "Prostatectomy slide". Each modality is an array with 0 or more representations. Within a representation there are always the same number of features.
- Kind
- Anything
- Read from
-
/input/prostate-modality-level-neural-representations.json
- Example file
- Download an example.
- Example value
-
{
"MRI image": [
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]
}
Prostate Modality-Level Neural Representations
-
- Slug
prostate-biopsy-decision-clinical-data- Description
- Clinical data that is relevant for prostate biopsy decision making
- Kind
- Anything
- Read from
-
/input/prostate-biopsy-decision-clinical-data.json
- Example file
- Download an example.
- Example value
-
{
"psa_trend": [
{
"val": 3.0,
"date": "Aug 2022"
},
{
"val": 2.5,
"date": "Nov 2023"
},
{
"val": 5.2,
"date": "Jan 2025"
}
],
"family_history": "No",
"previous_notes": [
{
"date": "08 Feb 2023",
"text": "An initial PSA reading of 2.2 ng/mL was recorded in August 2022. Subsequent testing in December revealed an increase to 3.8 ng/mL. Digital rectal examination remained unremarkable.",
"author": "Dr. T. Hendriks (GP)"
},
{
"date": "02 Jun 2024",
"text": "Following the first biopsy results, PSA levels advanced to 4.2 ng/mL. Mild urinary frequency is reported, without notable obstruction. Persistent biochemical elevation and the earlier histological findings were documented.",
"author": "Dr. T. Hendriks (GP)"
}
],
"radiology_report": "Multiparametric MRI Prostate | 15 January 2025 | Amsterdam UMC, AMC\n\nClinical context: Ascending PSA (5.2 ng/mL) alongside a previously documented positive biopsy bucket. Prior imaging carried a PI-RADS 4 designation.\n\nFINDINGS: Prostate volume registers at 34.49 mL. A discrete hypointense focus occupies the right anterior mid-gland, spanning roughly 12 x 9 x 10 mm on T2-weighted sequences. DWI shows pronounced restricted diffusion paired with notably low ADC values. Early focal enhancement characterizes the DCE sequences. The peripheral zone remains clear. Extraprostatic extension and seminal vesicle invasion are absent. Pelvic lymphadenopathy is not present.\n\nIMPRESSION: PI-RADS 4 lesion in the right anterior mid-gland. Prostate volume 34.49 mL. PSAD 0.151 ng/mL/mL. csPCa predicted probability 0.5618297.",
"laboratory_results": [
{
"val": "5.2 ng/mL",
"date": "30 Dec 2024",
"flag": "H",
"name": "PSA"
},
{
"val": "1.24 ng/mL",
"date": "30 Dec 2024",
"flag": "",
"name": "Free PSA"
},
{
"val": "24%",
"date": "30 Dec 2024",
"flag": "",
"name": "%Free PSA"
},
{
"val": "12.4 g/dL",
"date": "30 Dec 2024",
"flag": "L",
"name": "Haemoglobin"
},
{
"val": "9.1 x10^9/L",
"date": "30 Dec 2024",
"flag": "",
"name": "WBC"
},
{
"val": "258 x10^9/L",
"date": "30 Dec 2024",
"flag": "",
"name": "Platelets"
},
{
"val": "88 umol/L",
"date": "30 Dec 2024",
"flag": "",
"name": "Creatinine"
},
{
"val": ">60 mL/min/1.73m2",
"date": "30 Dec 2024",
"flag": "",
"name": "eGFR"
},
{
"val": "17.7 nmol/L",
"date": "30 Dec 2024",
"flag": "",
"name": "Testosterone"
},
{
"val": "69 U/L",
"date": "30 Dec 2024",
"flag": "",
"name": "Alkaline phosphatase"
},
{
"val": "209 U/L",
"date": "30 Dec 2024",
"flag": "",
"name": "LDH"
}
]
}
Prostate Biopsy Decision Clinical Data
|
-
- Slug
prostate-biopsy-decision- Description
- Decision to biopsy a prostate ("yes"/"no").
- Kind
- Anything
- Write to
-
/output/prostate-biopsy-decision.json
- Example file
- Download an example.
- Example value
-
"yes"
Prostate Biopsy Decision
-
- Slug
prostate-biopsy-decision-reasoning- Description
- Reasoning behind the biopsy decision, capture in a structured format.
- Kind
- Anything
- Write to
-
/output/prostate-biopsy-decision-reasoning.json
- Example file
- Download an example.
- Example value
-
{
"free_text": "The decision is driven by three critical factors: the PI-RADS 5 score, the extremely high csPCa predicted probability (0.96), and the frankly elevated PSA level (187.0 ng/mL) with a rapid upward trend.",
"confidence": "clear",
"variable_weights": {
"bx": "decisive",
"fh": "noted",
"age": "important",
"dre": "noted",
"psa": "noted",
"vol": "noted",
"psad": "not_used",
"cspca": "not_used",
"pirads": "important",
"comorbidity": "noted"
}
}
Prostate Biopsy Decision Reasoning
|
| 2 |
-
- Slug
structured-prompt- Description
- A (JSON) structured prompt that orchestrates an algorithm.
- Kind
- Anything
- Read from
-
/input/structured-prompt.json
- Example file
- Download an example.
- Example value
-
{
"key": "value",
"None": null
}
Structured Prompt
-
- Slug
prostate-modality-level-neural-representations- Description
- A collection of optional neural representations of prostate-related modalities. Contains "MRI image", "Biopsy slide" and/or "Prostatectomy slide". Each modality is an array with 0 or more representations. Within a representation there are always the same number of features.
- Kind
- Anything
- Read from
-
/input/prostate-modality-level-neural-representations.json
- Example file
- Download an example.
- Example value
-
{
"MRI image": [
[
0.28736573457717896,
-2.8309085369110107,
0.9847686290740967,
0.7872962355613708,
-0.5533920526504517,
0.2100987434387207,
-3.637934446334839,
-1.4421955347061157,
-1.516884446144104,
-0.9484667181968689,
1.5990962982177734,
-0.40520384907722473,
-3.123274326324463,
-0.9095510840415955,
-1.7861841917037964,
3.5617599487304688,
1.0177569389343262,
-0.6886646747589111,
0.5718612670898438,
-0.14440470933914185,
-1.260922908782959,
-3.212146759033203,
-1.3721009492874146,
-2.0848677158355713,
-1.1688926219940186,
-1.812921404838562,
-3.5757312774658203,
-2.120961904525757,
-0.08772245794534683,
-3.6728551387786865,
-0.1706904023885727,
-2.9247183799743652,
-0.985244631767273,
-1.8596283197402954,
-1.2401604652404785,
-1.062150001525879,
-2.0076584815979004,
-2.298478126525879,
-0.8217303156852722,
-0.8734867572784424,
-1.7123159170150757,
-1.6244889497756958,
-1.1467125415802002,
-1.6429994106292725,
1.1541191339492798,
-3.229480743408203,
0.934668779373169,
-2.4095001220703125,
0.14767438173294067,
-1.440678358078003,
-2.1039562225341797,
-0.16500188410282135,
-2.99228835105896,
-0.3602313995361328,
-1.545637845993042,
-1.3117611408233643,
-1.9626719951629639,
-3.8583929538726807,
-3.0352344512939453,
-0.1751147359609604,
-0.09008651971817017,
-1.04323148727417,
-0.858181357383728,
-1.3516048192977905,
-1.4700562953948975,
-1.2247034311294556,
-1.5221360921859741,
-0.7437664270401001,
0.10551246255636215,
-0.7587389349937439,
-0.22538982331752777,
-1.8970502614974976,
-1.033363938331604,
-1.1343673467636108,
-1.5830118656158447,
-1.8149510622024536,
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1.1340292692184448,
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1.2136934995651245,
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3.1391353607177734,
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-1.0398449897766113,
-1.0339784622192383,
-1.263484001159668,
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-0.8685362339019775,
-0.5482903122901917,
-0.7103097438812256,
-2.9270834922790527,
-1.3334108591079712,
-1.0702916383743286,
-0.8974400162696838,
3.2481839656829834,
-2.196741819381714,
-2.518242597579956,
-0.8990381956100464,
1.8351995944976807,
-4.538361072540283,
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]
}
Prostate Modality-Level Neural Representations
-
- Slug
prostate-treatment-decision-clinical-data- Description
- Clinical data that is relevant for prostate treatment decision making
- Kind
- Anything
- Read from
-
/input/prostate-treatment-decision-clinical-data.json
- Example file
- Download an example.
- Example value
-
{
"psa_trend": [
{
"val": 17.4,
"date": "Feb 2024"
},
{
"val": 10.2,
"date": "Jun 2024"
},
{
"val": 0.5,
"date": "Oct 2024"
},
{
"val": 187.0,
"date": "Feb 2025"
}
],
"family_history": "No",
"previous_notes": [
{
"date": "19 Feb 2023",
"text": "Patient presented with elevated PSA of 17.4 ng/mL in February 2023. Digital rectal examination was unremarkable. Multiparametric MRI was arranged, showing a PI-RADS 5 lesion in the right peripheral zone. Transperineal biopsy was performed, revealing Gleason 4+4 (ISUP grade group 4) adenocarcinoma with cribriform pattern and perineural invasion. The patient was referred to urology for further management discussion. At that time, he opted for active surveillance after reviewing the risks and benefits of immediate intervention, citing his age and comorbidities. Follow-up PSA was scheduled for six months later.",
"author": "Dr. H. Martens (GP)"
}
],
"pathology_report": "Biopsy specimen, 19 Feb 2023:\nHistological examination reveals adenocarcinoma of the prostate. The Gleason score is 4+4, corresponding to ISUP grade group 4. The tumour exhibits a predominant cribriform growth pattern. Perineural invasion is present. The tumour is located in the seminal vesicles, right.\n\nSummary of trajectory:\nThe histological findings across the single documented biopsy timepoint demonstrate high-grade disease with cribriform architecture and perineural invasion, consistent with aggressive biological behaviour.\n\nAI-predicted ISUP grade group (digital pathology): grade group 5.",
"radiology_report": "Spaarne Gasthuis (Haarlem)\nRadiology Dept\nDate: 20 Jan 2025\nExam: mpMRI prostate\n\nClinical indication: Rising PSA (187.0 ng/mL), prior biopsy Gleason 4+4, evaluate for local extent and suspicious lesions.\n\nFINDINGS:\nProstate volume: 57.28 mL.\nT2-weighted imaging demonstrates a focal, ill-defined hypointense lesion in the right peripheral zone, extending towards the right seminal vesicle. On diffusion-weighted imaging, the lesion shows marked restricted diffusion with high signal intensity on b=1400 images and corresponding low ADC values. Dynamic contrast-enhanced sequences reveal early, intense enhancement of the lesion relative to the surrounding glandular tissue. The right seminal vesicle shows asymmetrical enlargement and signal alteration consistent with tumour infiltration. No suspicious lymphadenopathy or bone lesions are identified within the field of view.\n\nIMPRESSION:\nPI-RADS 5 lesion in the right peripheral zone with seminal vesicle involvement.\nProstate volume 57.28 mL; PSA density 3.26 ng/mL/mL.\nClinical stage cT1c.\ncsPCa predicted probability 0.964853.",
"laboratory_results": [
{
"val": "187.0 ng/mL",
"date": "09 Jan 2025",
"flag": "H",
"name": "PSA"
},
{
"val": "27.75 ng/mL",
"date": "09 Jan 2025",
"flag": "",
"name": "Free PSA"
},
{
"val": "15%",
"date": "09 Jan 2025",
"flag": "L",
"name": "%Free PSA"
},
{
"val": "14.9 g/dL",
"date": "09 Jan 2025",
"flag": "",
"name": "Haemoglobin"
},
{
"val": "3.9 x10^9/L",
"date": "09 Jan 2025",
"flag": "",
"name": "WBC"
},
{
"val": "331 x10^9/L",
"date": "09 Jan 2025",
"flag": "",
"name": "Platelets"
},
{
"val": "102 umol/L",
"date": "09 Jan 2025",
"flag": "",
"name": "Creatinine"
},
{
"val": ">60 mL/min/1.73m2",
"date": "09 Jan 2025",
"flag": "",
"name": "eGFR"
},
{
"val": "11.4 nmol/L",
"date": "09 Jan 2025",
"flag": "",
"name": "Testosterone"
},
{
"val": "75 U/L",
"date": "09 Jan 2025",
"flag": "",
"name": "Alkaline phosphatase"
},
{
"val": "200 U/L",
"date": "09 Jan 2025",
"flag": "",
"name": "LDH"
}
]
}
Prostate Treatment Decision Clinical Data
|
-
- Slug
prostate-treatment-decision- Description
- Decision to treat prostate. Any of: active_surveillance / continued_surveillance / active_treatment /watchful_waiting
- Kind
- Anything
- Write to
-
/output/prostate-treatment-decision.json
- Example file
- Download an example.
- Example value
-
"watchful_waiting"
Prostate Treatment Decision
-
- Slug
prostate-treatment-decision-reasoning- Description
- Reasoning for the decision on treatment of the prostate. Structured format.
- Kind
- Anything
- Write to
-
/output/prostate-treatment-decision-reasoning.json
- Example file
- Download an example.
- Example value
-
{
"free_text": "The decision to proceed to active treatment is driven primarily by the confluence of high-grade pathology (Gleason 4+4 with PNI), high-risk imaging findings (PI-RADS 5 with seminal vesicle invasion), and aggressive biochemical progression indicated by the rapid PSA escalation.",
"confidence": "clear",
"variable_weights": {
"ct": "important",
"fh": "noted",
"age": "important",
"psa": "important",
"psad": "noted",
"cspca": "noted",
"pirads": "decisive",
"bx_isup": "decisive",
"bx_gl_sec": "noted",
"bx_gl_prim": "noted",
"comorbidity": "noted"
}
}
Prostate Treatment Decision Reasoning
|
| 3 |
-
- Slug
structured-prompt- Description
- A (JSON) structured prompt that orchestrates an algorithm.
- Kind
- Anything
- Read from
-
/input/structured-prompt.json
- Example file
- Download an example.
- Example value
-
{
"key": "value",
"None": null
}
Structured Prompt
-
- Slug
prostate-modality-level-neural-representations- Description
- A collection of optional neural representations of prostate-related modalities. Contains "MRI image", "Biopsy slide" and/or "Prostatectomy slide". Each modality is an array with 0 or more representations. Within a representation there are always the same number of features.
- Kind
- Anything
- Read from
-
/input/prostate-modality-level-neural-representations.json
- Example file
- Download an example.
- Example value
-
{
"MRI image": [
[
0.28736573457717896,
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0.9847686290740967,
0.7872962355613708,
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-3.637934446334839,
-1.4421955347061157,
-1.516884446144104,
-0.9484667181968689,
1.5990962982177734,
-0.40520384907722473,
-3.123274326324463,
-0.9095510840415955,
-1.7861841917037964,
3.5617599487304688,
1.0177569389343262,
-0.6886646747589111,
0.5718612670898438,
-0.14440470933914185,
-1.260922908782959,
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-3.6728551387786865,
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-1.8596283197402954,
-1.2401604652404785,
-1.062150001525879,
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-2.298478126525879,
-0.8217303156852722,
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-1.7123159170150757,
-1.6244889497756958,
-1.1467125415802002,
-1.6429994106292725,
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-3.8583929538726807,
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-1.04323148727417,
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-1.3516048192977905,
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]
}
Prostate Modality-Level Neural Representations
-
- Slug
prostate-time-to-recurrence-or-last-follow-up-clin- Description
- Clinical data that is relevant for predicting time (months) to either recurrence or last follow up.
- Kind
- Anything
- Read from
-
/input/prostate-time-to-recurrence-or-last-follow-up-clinical-data.json
- Example file
- Download an example.
- Example value
-
{
"family_history": "There is no family history of prostate or breast cancer.",
"previous_notes": "The patient is not on 5-ARI medication. No relevant comorbidities recorded, with a Charlson Comorbidity Index (CCI) of 3.",
"pathology_report": "The patient underwent one biopsy session. At biopsy, Gleason 4+4 (ISUP grade group 4, AI model-predicted ISUP 5) was identified in the left base; cribriform pattern was present. The reported histological growth pattern was: Adenocarcinoma.",
"radiology_report": "Prostate volume: 37.29 cc. PSA density: 2.306 ng/mL/cc. PI-RADS: 5. AI model-predicted probability of clinically significant prostate cancer (0\u20131): 0.9527162.",
"surgical_pathology_report": "The robot-assisted radical prostatectomy specimen showed Gleason 4+3 (ISUP grade group 3), pathological stage pT4b. Extraprostatic extension was present; surgical margins were positive; the seminal vesicles were invaded; lymphovascular invasion was absent; lymph node metastasis was present."
}
Prostate Time to Recurrence or Last Follow-Up Clinical Data
|
-
- Slug
prostate-time-to-recurrence-or-last-follow-up-reas- Description
- Reasoning that is used to predict the months to recurrence or last follow-up.
- Kind
- String
- Write to
-
/output/prostate-time-to-recurrence-or-last-follow-up-reasoning.json
- Example file
- Download an example.
- Example value
-
"High-risk pathology (lymph node metastasis, pT4b), positive surgical margins, and seminal vesicle invasion drive the prediction. These aggressive features significantly elevate the immediate risk of biochemical recurrence post-radical prostatectomy."
Prostate Time to Recurrence or Last Follow-Up Reasoning
-
- Slug
prostate-time-to-recurrence-or-last-follow-up- Description
- Report on months to recurrence (or last follow-up) together with event (0/1).
- Kind
- Anything
- Write to
-
/output/prostate-time-to-recurrence-or-last-follow-up.json
- Example file
- Download an example.
- Example value
-
{
"event": 0,
"months_to_recurrence": 31.4
}
Prostate Time To Recurrence or Last Follow-Up
|
