PUMA: Panoptic segmentation of nUclei and tissue in MelanomA

The PUMA Challenge aims to enhance nuclei and tissue segmentation in melanoma histopathology, addressing the need for better prognostic biomarkers to predict treatment responses. Melanoma, a highly aggressive skin cancer, often requires immune checkpoint inhibition therapy, but only half of patients respond. Prognostic biomarkers like tumor infiltrating lymphocytes (TILs) correlate with better therapy responses and lower recurrence rate, but manual TIL scoring is subjective and inconsistent. Current deep learning methods underperform. The PUMA dataset includes annotated primary and metastatic melanoma regions to improve segmentation techniques. The challenge includes two tracks with tasks focused on tissue and nuclei segmentation, encouraging advanced methods to improve predictive accuracy.

TrackRad: Real-time tumor tracking for MRI-guided radiotherapy

The LUNA25 Challenge

PANTHER Challenge

Automated Identification of Mod-Sev TBI Lesions 2025